Sona Ajit Chikarmane MD, Presenter: Nothing to Disclose

Eva Csilla Gombos MD, Abstract Co-Author: Royalties, Amirsys, Inc

Angela A. Giardino MD, Abstract Co-Author: Nothing to Disclose

RAA is an aggressive malignancy that can develop years after breast irradiation and may be difficult to detect clinically in a background of radiation-induced skin changes; RAA may also be obscured by expected post-treatment changes (e.g. architectural distortion, skin thickening) on conventional imaging (mammogram and ultrasound[US]). Earlier detection and treatment has been shown to improve survival. The purpose of this exhibit is to 1) review the pathology and demographics of RAA, 2) demonstrate the role of imaging in the diagnosis and management of RAA and 3) illustrate challenging cases with emphasis on multimodality imaging.

1. Review demographics, clinical presentation, and pathology of patients with RAA 2. Illustrate how imaging (mammography, US, and breast/chest wall magnetic resonance imaging [MRI]) is used in diagnosing RAA, with emphasis on MRI 3. Highlight role of imaging in staging, surgical planning, treatment response, and detecting recurrences/metastases  4. Discuss a multidisciplinary approach to treatment and management, focusing on conventional chemotherapies, new molecular targeted therapies and surgical options  5. Review challenging cases of RAA on mammography, US, and MRI, ranging from initial diagnosis to metastatic patterns, and draw examples from our tertiary care cancer center’s radiology & pathology database 

http://abstract.rsna.org/uploads/2014/14008094/14008094_mnf2.pdf

Chikarmane, S, Gombos, E, Giardino, A, Diagnosis, Treatment, and Follow-Up of Radiation Associated Angiosarcoma (RAA) of the Breast – What Radiologists Need to Know.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14008094.html