Posy Jane Seifert DO, Presenter: Nothing to Disclose

Renee Morgan RT, Abstract Co-Author: Nothing to Disclose

Andrea Lynn Arieno BS, Abstract Co-Author: Nothing to Disclose

To prove the efficacy of using a BCT guided breast biopsy bracket system for lesion retrieval in phantom and subject studies. 

Under IRB approval, 45 phantom biopsy studies were performed using the BCT-GBx bracket system. This consisted of small, medium, and large phantoms with 50%/50% glandular and adipose background composition. Each phantom contained 10 masses and 5 calcification clusters of varying sizes. All phantoms were biopsied under both BCT and stereotactic guidance following an imaging protocol. Post biopsy imaging was performed in all cases to confirm lesion retrieval. Dose comparison for phantom imaging was recorded for both modalities. After successful completion of phantom studies, 4 subjects consented to have breast lesions biopsied with the BCT-GBx bracket system. Subject data consisted of breast density, lesion characterizations, size, imaging-pathologic concordance and results of open surgical biopsy if performed.

Phantom mass and calcium retrieval was 100% for both BCT-GBx and stereotactic biopsy, evidenced by a specimen radiograph. Dose was found to be equivalent to or less than the standard stereotactic approach. Four subjects with masses; with an average size of 3.4 cm (range 2.3 to 4.8 cm), were successfully biopsied and had pathology results concordant with imaging. 

Initial experience with BCT-GBx bracket system has shown to be equivalent to stereotactic biopsy in phantom studies with equivalent or decreased dose. Preliminary BCT subject biopsies show concordance to imaging.

Breast CT is a new technology that may identify lesions not seen by other imaging modalities; CT guided breast biopsy may be necessary for diagnosis.

Seifert, P, Morgan, R, Arieno, A, Initial Experience with a Breast Computed Tomography Guided Biopsy System (BCT-GBx) for Cone Beam Breast CT (CBBCT).  Radiological Society of North America 2013 Scientific Assembly and Annual Meeting, December 1 - December 6, 2013 ,Chicago IL. http://archive.rsna.org/2013/13044191.html