Seyed Mohammad Mehdi Ameli Renani MBBS, Presenter: Nothing to Disclose

Laurie Ramsay BMBCh, Abstract Co-Author: Nothing to Disclose

Farzana Mehzabin Rahman FRCR, MBBS, Abstract Co-Author: Nothing to Disclose

Arjun Nair MBBCh, FRCR, Abstract Co-Author: Nothing to Disclose

Anand Devaraj MBBS, Abstract Co-Author: Nothing to Disclose

Ioannis Vlahos MRCP, FRCR, Abstract Co-Author: Consultant, Siemens AG Consultant, General Electric Company

Veronica Smith MBBCh, MRCP, Abstract Co-Author: Nothing to Disclose

Brendan P. A. Madden MBBCh, MD, Abstract Co-Author: Nothing to Disclose

To illustrate the potential value of DECT in the evaluation of patients with PH.

PH tertiary referral center experience: • Brief DECT applicable techniques: low kVp, pulmonary blood volume (PBV) and iodine mapping • Technical details that can affect image quality and cause erroneous interpretation Low threshold (-960HU), impact of emphysema High threshold (-600HU) impact of ground glass, emphysema, ILD FOV limitations Technical adaptations to avoid above • Explanation of PBV variability between different causes of PH • Significance and relationship of ground glass, mosaicism and PBV, DECT V/Q • CTEPH appearance, differences and progression from simple PE • Occlusive v non-occlusive PE at PBV, physiology impact • Right ventricle enhancement Iodine mapping • Central vs peripheral enhancement differences and PBV variability between PH and non PH populations • Relationship of PBV to PVR • Evolving PBV usage: Characterising disease Central/PBV enhancement ratios and PBV variability for detecting PH in combination with morphological features or directing/monitoring therapy.

This exhibit depicts the current and future potential of DECT to evaluate PH while avoiding several commonly unrecognized pitfalls that can affect interpretation of DECT images in these patients.

Ameli Renani, S, Ramsay, L, Rahman, F, Nair, A, Devaraj, A, Vlahos, I, Smith, V, Madden, B, Dual Energy CT (DECT) Imaging for Pulmonary Hypertension (PH): Challenges and Opportunities.  Radiological Society of North America 2012 Scientific Assembly and Annual Meeting, November 25 - November 30, 2012 ,Chicago IL. http://archive.rsna.org/2012/12031228.html