Arjun Nair MBCHB, FRCR, Presenter: Nothing to Disclose

Brendan Tinwell MBBS, Abstract Co-Author: Nothing to Disclose

John Du Parcq MBBS, Abstract Co-Author: Nothing to Disclose

Anand Devaraj MBBS, Abstract Co-Author: Nothing to Disclose

Sisa Grubnic MD, Abstract Co-Author: Nothing to Disclose

Ioannis Vlahos MBBS, Abstract Co-Author: Researcher, Siemens AG Consultant, Siemens AG Consultant, General Electric Company Consultant, Medicsight, Inc

Multidisciplinary proposals for the significant revision of the pathological classification of lung adenocarcinoma have recently been published by the IASLC, ATS and ERS. We aim to:   Summarize the key changes in nomenclature and their underpinning rationale Illustrate their radiological appearances with pathological correlation  

Revision rationale (e.g. survival/treatment of subsolid lesions, molecular and therapeutic advances e.g. EGFR mutations) Classification changes (e.g. elimination of bronchioloalveolar carcinoma, introduction of adenocarcinoma in situ, minimally invasive adenocarcinoma) CT appearances of new entities (histological old/new term correlations) T staging implications (solid v ground glass), CAD, biopsy material Radiological follow-up: guidance, lesion evolution, multifocal lesions    

The major teaching points are: Awareness of new integrative proposals based on the biology and evolution of subsolid lung adenocarcinoma. Abolition of BAC and introduction of precursor-type lesions which will require further TNM revisions. Interim recommendations to classify subsolid lesions, for radiological staging and observation, and an awareness of the contemporary nomenclature and its management implications will assist radiologists in providing more clinically relevant reports.

Nair, A, Tinwell, B, Du Parcq, J, Devaraj, A, Grubnic, S, Vlahos, I, Proposed Clinical, Pathological, and Radiological Revisions to the Classification of Lung Adenocarcinoma: Radiological Implications with Pathological Correlation.  Radiological Society of North America 2011 Scientific Assembly and Annual Meeting, November 26 - December 2, 2011 ,Chicago IL. http://archive.rsna.org/2011/11001508.html