Microsimulation models synthesize available information about disease processes and interventions, including results from randomized controlled trials, observational and epidemiologic studies, and expert opinion. This synthesis is the product of a structured model, which itself incorporates expert opinion. In this presentation, I will review basics of microsimulation models with a focus on methods for their evaluation and assessment, including comparative modeling efforts supported by the National Cancer Institute. I will also point toward efforts to improve model assessment, touching on technological advances and actions that radiologist-researches can make to improve models. These ideas will be demonstrated using a model for colorectal cancer that was used in a recent USPSTF analysis of CT colonograpy.
Rutter, C,
Health Services Policy and Research Keynote Speaker: Microsimulation Models—Synthesizing Evidence for Policy Makers. Radiological Society of North America 2010 Scientific Assembly and Annual Meeting, November 28 - December 3, 2010 ,Chicago IL.
http://archive.rsna.org/2010/9020285.html