Rajesh Kumar MS, Presenter: Nothing to Disclose

Mario Giardini PhD, Abstract Co-Author: Nothing to Disclose

Ifor Samuel, Abstract Co-Author: Nothing to Disclose

Kishan Dholakia, Abstract Co-Author: Nothing to Disclose

Andreas Melzer MD, DDS, Abstract Co-Author: Consultant, INNOMEDIC GmbH, Herxheim, Germany Shareholder, INNOMEDIC GmbH, Herxheim, Germany

The purpose is to introduce the basic physical and technical principles of modern bio-photonic techniques and outline efficient potential clinical applications in the field of radiological imaging. We aim to find suitable Interventional imaging systems for early and safe in situ diagnosis of cancer and cardiovascular diseases.

Medical photonics provides a variety of optical technologies & instruments not only for diagnostic and imaging but also for surgical & therapeutic purposes. The current literature has been reviewed for application of the advanced Raman spectroscopy,optical coherence tomography,confocal microscopy,Photodynamic therapy with OLEDs,contrast-agents nano-particles & quantum-dots.Special attention has been paid to the need of integration of these techniques with imaging modalities: US, MRI and PET/CT.

Bio-photonics have made substantial progress for biology and the life sciences and, to date, are primarily used in preclinical research. There is however emerging field of clinical application i.e. Raman Spectroscopy & confocal microscopy in the field of skin & mucosal cancer & gastrointestinal endoscopy.Such novel embodiments of these techniques are targeting image guided interstitial applications with probes and combination of OCT, Raman with imaging modalities MRI,PET/CT & US are promising.

Kumar, R, Giardini, M, Samuel, I, Dholakia, K, Melzer, A, Bio-photonic Techniques: Physical Principles and Potential Applications in Radiology.  Radiological Society of North America 2010 Scientific Assembly and Annual Meeting, November 28 - December 3, 2010 ,Chicago IL. http://archive.rsna.org/2010/9014996.html