Christina Louise Tosti PhD, Presenter: Nothing to Disclose

Jeffrey Steinberg, Abstract Co-Author: Nothing to Disclose

Steffen Sammet MD, PhD, Abstract Co-Author: Nothing to Disclose

Jun Zhang PhD, Abstract Co-Author: Nothing to Disclose

Guang Jia PhD, Abstract Co-Author: Nothing to Disclose

Michael Vinzenz Knopp MD, PhD, Abstract Co-Author: Nothing to Disclose

Zhiqiang Hu, Abstract Co-Author: Employee, Koninklijke Philips Electronics NV

Jeffrey Kaste, Abstract Co-Author: Employee, Koninklijke Philips Electronics NV

Patrick Burns, Abstract Co-Author: Nothing to Disclose

The development of robust MR-based attenuation correction methodology is necessary to make combined MR/PET imaging clinically relevant. The purpose of this exhibit is to introduce the existing MR-based attenuation correction (MRAC) techniques and compare those to the capabilities of transmission and CT-based methods.

1.) Traditional attenuation correction (AC) methods: Transmission-based AC and CT-based AC 2.) MR-based AC Acquisitions: Sequences for 3-compartment and 4-compartment segmentation 3.) MR-based AC Post-processing: Segmentation and atlas-based methods  

The major teaching points of this exhibit are: 1.) A necessary step to establish PET/MR in clinical practice is the development of robust attenuation correction methodology. 2.) MR cannot directly measure the attenuation of photons in tissue. However, using established characteristics for specific tissue types, an attenuation map equivalent can be determined. 3.) MR-based attenuation correction methods are evolving to be sufficient for clinical hybrid imaging and quantitative evaluation.

Tosti, C, Steinberg, J, Sammet, S, Zhang, J, Jia, G, Knopp, M, Hu, Z, Kaste, J, Burns, P, MR-based Attenuation Correction for MR/PET Imaging: The State of the Art.  Radiological Society of North America 2010 Scientific Assembly and Annual Meeting, November 28 - December 3, 2010 ,Chicago IL. http://archive.rsna.org/2010/9000225.html