Ji-young Hwang MD, Presenter: Nothing to Disclose

Eun Young Ko MD, PhD, Abstract Co-Author: Nothing to Disclose

Boo-Kyung Han MD, PhD, Abstract Co-Author: Nothing to Disclose

Jung Hee Shin MD, Abstract Co-Author: Nothing to Disclose

Seok Seon Kang MD, Abstract Co-Author: Nothing to Disclose

Soo Yeon Hahn MD, Abstract Co-Author: Nothing to Disclose

Mee Young Nam MD, Abstract Co-Author: Nothing to Disclose

To evaluate the characteristic MR findings of high grade ductal carcinoma in 냐셔 (DCIS) which differentiate high from low grade DCIS  

From January 2007 to December 2008, 253 patients were diagnosed as pure DCIS after breast cancer surgery. Preoperative breast MRI was performed for 213 patients. After excluding the patients who had no residual cancer after surgery (n=21) and the patients who had DCIS less than 1cm extent (n=34), 162 DCIS in 162 patients were finally enrolled in this study including four patients with bilateral DCIS. Two breast dedicated radiologists retrospectively reviewed MR images without information of histological results with considering the mammographic and sonographic findings. We analyzed enhancement type (mass / non-mass), kinetics (presence of early enhancement and washout), and extent of the lesions. In the non-mass lesions, we divided them by diffuse/regional, segmental/ductal, and focal/solitary type. We compared the difference of the extent of lesions between preoperative MRI and final pathologic results.  

High grade DCIS showed non-mass enhancement in 82.7%, and low grade DCIS showed 68.5%. Extent of the lesion was significantly larger in high grade DCIS. Low grade DCIS showed much smaller extent on MRI compared with pathologic results. Washout pattern was noted in 18/52 (34.6%) of high grade and 9/89 (10.1%) of low grade DCIS. Negative MR finding was noted in 6/52 (11.5%) of high grade and 14/59 (23.7%) of low grade DCIS.  

Large extent of non-mass enhancement, and washout enhancement pattern suggests high grade DCIS.  

Large extent of non-mass enhancement, and washout enhancement pattern suggests high grade DCIS.  

Hwang, J, Ko, E, Han, B, Shin, J, Kang, S, Hahn, S, Nam, M, Different MR Findings of High and Low Grade Ductal Carcinoma in Situ.  Radiological Society of North America 2009 Scientific Assembly and Annual Meeting, November 29 - December 4, 2009 ,Chicago IL. http://archive.rsna.org/2009/8016699.html