RSNA 2008 

Abstract Archives of the RSNA, 2008


SST08-07

Clear Cell Renal Cell Carcinoma: Contrast-enhanced Ultrasound Features Relation to Tumor Size

Scientific Papers

Presented on December 5, 2008
Presented as part of SST08: Genitourinary (Ultrasound)

Participants

Yaqing Chen PhD, Presenter: Nothing to Disclose
Jun Jiang, Abstract Co-Author: Nothing to Disclose
Yongchang Zhou, Abstract Co-Author: Nothing to Disclose

PURPOSE

To analyze the contrast-enhanced ultrasound (CEUS) features of clear cell renal cell carcinoma (CCRCC) in relation to tumor size.

METHOD AND MATERIALS

The CEUS appearance of 92 CCRCCs confirmed pathologically were retrospectively analyzed. Tumor size was stratified into six groups with a 1cm interval. For each lesion, the degree of enhancement, the homogeneity of enhancement and the presence of pseudocapsule sign were evaluated.

RESULTS

The tumors of groupⅠto Ⅵ was counted for 13, 26, 21, 11, 10 and 11, respectively. All the CCRCCs mainly showed a marked enhancement, and there was no statistically significance between the degree of enhancement and tumor size (P>0.05). However, both homogeneity of enhancement and presence of pseudocapsule correlated well with the tumor size (P<0.01). Homogeneous enhancement was shown in 85%, 65%, 19%, 9%, 0 and 0 of the tumors in the six groups, respectively. In tumors ≤3cm the frequency (72%) of homogeneity was significantly higher than in tumors >3cm (9%; P<0.01). The detection rate of pseudocapsule sign in the six group was 23%, 62%, 71%, 64%, 50% and 0, respectively. The frequency of pseudocapsule sign was significantly higher in tumors 2.1-5 cm than <2cm and >5cm (66%, 23%, 24%, respectively; P<0.01).

CONCLUSION

CEUS features of CCRCCs vary with the size of the tumor, especially in the homogeneity of enhancement and the presence of pseudocapsule sign. CEUS is effective in demonstrating the sonographic visualization of tumoral characteristics.

CLINICAL RELEVANCE/APPLICATION

CEUS can clearly demonstrate the perfusion characteristics of CCRCCs, it provides more information for the ultrasonographic diagnosis of renal tumors.

Cite This Abstract

Chen, Y, Jiang, J, Zhou, Y, Clear Cell Renal Cell Carcinoma: Contrast-enhanced Ultrasound Features Relation to Tumor Size.  Radiological Society of North America 2008 Scientific Assembly and Annual Meeting, February 18 - February 20, 2008 ,Chicago IL. http://archive.rsna.org/2008/6017577.html