Mizuki Nishino MD, Presenter: Nothing to Disclose

Harumi Itoh MD, Abstract Co-Author: Nothing to Disclose

Hiroto Hatabu MD, Abstract Co-Author: Nothing to Disclose

In this review, we provide a practical approach to HRCT of diffuse lung disease emphasizing distribution of abnormality; upper, middle and lower zones; central or peripheral; in relation to secondary pulmonary lobules, leading to narrower differential diagnoses.

Diffuse lung disease presents a variety of HRCT findings reflecting its complex pathology, and provides diagnostic challenge to radiologists. Frequent modification of detailed pathological classification makes it difficult to keep up with the latest understanding. We aim to describe a practical approach to the HRCT diagnosis of diffuse lung disease, emphasizing distribution of the abnormal findings throughout the lung; upper, middle and lower lung zones; central or peripheral; and distribution in relation to secondary pulmonary lobules. This simple approach leads to pin-point diagnosis or narrower differential diagnoses. Diffuse lung disease discussed in this review include IPF, NSIP, collagen vascular diseases, asbestosis, miliary TB, metastasis, sarcoidosis, lymphangitis carcinomatosa /lymphoma, HP, COP, etc. The HRCT findings are correlated with pathological findings to enhance understanding of the disease process and pathogenesis of imaging features.

Nishino, M, Itoh, H, Hatabu, H, A Practical Approach to High-Resolution CT of Diffuse Lung Disease.  Radiological Society of North America 2004 Scientific Assembly and Annual Meeting, November 28 - December 3, 2004 ,Chicago IL. http://archive.rsna.org/2004/4403984.html