Abstract:
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Purpose: to determine whether diffusion MR imaging of b = 2000 sec/mm2 is better than that of b = 1000 sec/mm2 for the detection of diffusion changes in hyper-acute ischemic stroke.
Methods and Materials: diffusion MR imaging was performed in 49 patients with hyper-acute ischemic stroke (within 6 hours after symptoms onset) by using a single-shot spin-echo EPI sequence with two different b values, 1000 and 2000 sec/mm2. Quantitative analysis of SNR, CNR, ADC and infarct volume measurement were done for selected regions of interest (ROIs) on the reconstructed isotropic diffusion weighted images and ADC maps.
Results: SNR and ADC value of the ROIs were significantly lower in b = 2000 images than in b = 1000 images (37.2 ± 10.1 vs. 42.4 ± 10.7, P < 0.01; 68.8 ± 13.9 vs.72.3 ± 14.9, P < 0.01, respectively) but CNR of the ROIs was significantly higher in b = 2000 images than in b = 1000 images (15.2 ± 9.1 vs.11.9 ± 7.6, P < 0.01). Measured infarct volume was significantly larger in b = 2000 images than in b = 1000 images (32.3 ± 43.1 vs. 22.2 ± 31.1, P < 0.01). Infarct volume measured on b = 2000 images was more close to that on follow-up diffusion MR images within 7 days (R = 0.793 in linear regression analysis).
Conclusion: diffusion weighted MR imaging of b = 2000 sec/mm2 is better than that of b = 1000 sec/mm in detecting hyper-acute ischemia induced diffusion changes.
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Kim MD, H,
Diffusion MR Imaging of Hyper-Acute Ischemic Stroke: Comparison between b = 1000 and b = 2000 Images at 1.5 Tesla System. Radiological Society of North America 2003 Scientific Assembly and Annual Meeting, November 30 - December 5, 2003 ,Chicago IL.
http://archive.rsna.org/2003/3106398.html
