Gabriela Melendez MD, Abstract Co-Author: Nothing to Disclose

Maricela Escuadra MD, Abstract Co-Author: Nothing to Disclose

Jorge Ignacio Magana MD, Presenter: Nothing to Disclose

Eulo Lupi, Abstract Co-Author: Nothing to Disclose

Aloha Meave, Abstract Co-Author: Nothing to Disclose

To determine the differences in the Cardiac Magnetic Resonance (CMR) findings between patients with idiopathic pulmonary hypertension (IPH) and those with PH associated with congenital heart disease (CHD).

This retrospective study included 39 patients with severe PH. Nineteen patients with IPH (18 women, mean age 41.4 ± 10 years) and 20 patients with PH associated with CHD (10 women, mean age 43.1 ± 16 years). There was no difference in the systolic pulmonary pressure: 91.9 ± 21.3 mm Hg in IPH versus 85.1 ± 15.5 mmHg in PH associated with CHD, p=0.26. All patients underwent a CMR study.

Right ventricular ejection fraction (RVEF) was lower in patients with IPH than in patients with PH associated with CHD (32.6 ± 10.3 vs 38.5 ± 10.8), although this difference was not statistically significant (p = 0.09). The RV mass, however, was significantly lower in IPH patients (63.1 ± 17.7 vs 85.9 ± 29.4, p=0.007) The left ventricular ejection fraction (LVEF) was significantly higher and left ventricular volumes and mass significantly lower in patients with PH associated with CHD vs IPH.

Patients with IPH had lower RV mass, higher LVEF, minor left mass and ventricular volumes.

Survival in patients with PH varies according to the etiology, being significantly better in patients with PH associated with CHD compared to IPH. The finding of this study, could explain the different prognosis between this 2 groups of patients with severe PH.

Melendez, G, Escuadra, M, Magana, J, Lupi, E, Meave, A, Differences in Biventricular Function Parameters and Mass in Patients with Idiopathic Pulmonary Hypertension compared with Pulmonary Hypertension Associated with Congenital Heart Disease.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14045799.html