Valeria Casali, Presenter: Nothing to Disclose

Marianna Telesca MD, Abstract Co-Author: Nothing to Disclose

Simone Liberali, Abstract Co-Author: Nothing to Disclose

Elena Miglio, Abstract Co-Author: Nothing to Disclose

Ilaria Mussetto, Abstract Co-Author: Nothing to Disclose

Federica Pediconi MD, Abstract Co-Author: Nothing to Disclose

David Cannata MD, Abstract Co-Author: Nothing to Disclose

Rossella Di Miscio, Abstract Co-Author: Nothing to Disclose

To investigate the role and the diagnostic accuracy of Breast Magnetic Resonance Imaging (MRI) in the evaluation of patients with suspeciuos discharge from the nipple.

68 patients with suspicious nipple discharge underwent MRI using a 1,5T scan with the following protocol: pre-contrast T2-weighted TIRM sequences, T1 weighted 3D sequences aquired before and after gadobenate dimeglumine administration (Multihance 0.1 mml/Kg). MRI findings were divided according to BIRADS creteria into two groups: benigns (BIRADS 1-2-3) and maligns (BIRADS 4-5). 42 patients underwent surgery, 26 patients were clinically and instrumentally followed-up during 24 months. Histological and clinical findings after 24 month were compared to MRI findings.

MRI identified 28 cases of BIRADS 4-5, 12 of which were found to be malignant at histological examination. In the 40 cases classified as BIRADS 1-2-3, 14 lesions were confirmed as benign by definitive histological examination, 2 lesions were found to be a malignant tumor and 24 patients had negative follow-up at 24 months. Sensitivity, specificity and diagnostic accuracy of MRI were respectively 93%, 92% and 92% with a positive predictive value of 87% and negative predictive value of 96%.

Breast MRI is an accurate method in the evaluation of patients with suspicious nipple secretion. A negative MRI can direct patients to follow-up rather than surgery.

Breast MRI can be considered a diagnostic leader in patients with unexplained nipple discharge to distinguish malignat from benign lesion.

Casali, V, Telesca, M, Liberali, S, Miglio, E, Mussetto, I, Pediconi, F, Cannata, D, Di Miscio, R, Diagnostic Accuracy of Breast MRI in the Evaluation of Patients with Suspicious Nipple Discharge..  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14045735.html