Nan Yan MMed, Presenter: Nothing to Disclose

Wang Chenwei PhD, Abstract Co-Author: Nothing to Disclose

Gemstone spectral CT can be substitute method for bone mineral density measurement.  

5 isolated fresh sheep lumbar vertebral body bone, including 4 vertebras for each bone, were used in this study. Each bone was scanned with both gemstone spectral CT (Discovery CT 750HD, GE healthcare) and DXA (Dual energy X-ray absorptiometry). Then, each bone got high temperature incineration and weighed, bone density was calculated. For CT data, monochromatic images were reconstructed; the bone calcium content was measured on quantitative calcium/water-based material decomposition images with a dedicated software (GSI Viewer). Using calcium content of bone ash as the gold standard, pearson correlation analysis was taken for the calcium content of GSI and BMD value of DXA are respectively.

Both calcium content of GSI and BMD value of DXA had high positive-correlation with calcium content of bone ash (both P<0.01). The correlation efficient of calcium content of GSI (r=0.888) was slight higher than that of BMD value of DXA(r=0.845).    

Quantitative calcium content measurement by gemstone spectral CT provide compatible accuracy with bone mineral density measurement of DXA.  

Gemstone spectral CT can be substitute method for bone mineral density measurement.  

Yan, N, Chenwei, W, Feasibility and Accuracy of Bone Density Measurement by CT Spectral Imaging: An in Vitro Study on Sheep Bone.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14045721.html