Che Ying MD, Presenter: Nothing to Disclose

Jung Hwan Baek, Abstract Co-Author: Nothing to Disclose

1.to compare and evaluate the difference and efficacy of two treatment methods of nodular goiter，radiofrequency ablation and thyroidectomy; 2.to evaluate the clinical application value of RFA on nodular goiter

200 nodular goiter patients underwent open surgery operation (group A) and 200 patients treated with radiofrequency ablation(group B)were selected and proceed one year of follow-up. The posttreatment complications, thyroid function, nodules residues and recurrence situation as well as hospital stays and cost were evaluated and compared.

The surgical complications incidence of group A was higher than that of group B (7.0%, 1.0%, P=0.002); 75.5% of the Group A patients removed more than 70% of their normal thyroid gland (unilateral or bilateral), 71.5% of whom need to exogenous thyroid hormone supplement, group B do not need the exogenous thyroid hormone; The focus were removed directly in group A group but inactivated in situ and absorbed gradually in group B with 12 months absorption rate 84.84±17.06%; The rate of multiple lesions residual nodules was 11.9% in group A and 2.9% in group B(P=0.004); One year recurrence rate was 2.5% in group A and 0.5% in group B, P=0.099, no statistically significant difference; Hospitalization days was 5-7 days of group A and 2-3 days of group B, the total cost was 15962.56±1073.27 yuan and 16535.78±2309.75 yuan in the above two groups but there was no statistically significant difference (P>0.05).

Both surgical resection and radiofrequency ablation are effective in the treatment of nodular goiter. Compared with surgery treatment, the radiofrequency ablation method shows the advantage of complete tumor inactivation, easy in operation, fewer complications, thyroid function maintenance, neck intact without scar, and shorter hospitalization time, which suggests a wide prospect of clinical application by this safe and effective minimally invasive treatment method.

Radiofrequency ablation is a safe, effective and minimal invasive treatment method of nodular goiter with a wide prospect of clinical application.

Ying, C, Baek, J, Preliminary Comparative Study between Thyroidectomy and Radiofrequency Ablation on Nodular Goiter.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14045642.html