Ruyi Bao MD, Presenter: Nothing to Disclose

Guanfu Liu MD, Abstract Co-Author: Nothing to Disclose

Zhiyong Li, Abstract Co-Author: Nothing to Disclose

Ying Ge MD, Abstract Co-Author: Nothing to Disclose

Ailian Liu MD, Abstract Co-Author: Nothing to Disclose

To quantitatively investigate pulmonary blood flow of main pulmonary artery and its changes induced by smoking with 3.0T phase-contrast MR imaging (PC-MRI).

Ten smokers with smoking history more than 25 years and ten non-smokers, who all were man in middle age and had no detectable intrinsic lung and heart disease, underwent PC-MRI of main pulmonary artery. Main measurement parameters included peak positive velocity, average flow, average positive flow and distensibility on Report Card 4.0 software. We quantitatively evaluated Hemodynamic changes of pulmonary artery between smokers and non-smokers.

Average flow (62.16±8.83ml/beat) and average positive flow (65.94±9.27ml/beat) of main pulmonary artery in smokers group were significantly lower than these (86.90±9.29 and 93.30±8.07 ml/beat) in non-smokers group, (t=-3.93, p=0.02; t=-4.70, p=0.01). Meanwhile, Peak positive velocity (98.33±29.29cm/s) and distensibility (33.44±4.46) of main pulmonary artery in smokers group were also lower than these (124.33±34.29cm/s and 40.43±20.03) in non-smokers group, but there were no statistical differences between them (t=1.14, P=0.29; t=0.84, P=0.41).

The findings of this study suggest that PC-MRI may reflect pulmonary blood flow change induced by smoking, which is useful to quantitatively evaluate and monitor pulmonary blood flow change in smokers.

A better quantitative evaluation of the pathophysiological change of pulmonary circulation induced by smoking helps to monitor pulmonary hypertension and guide smoking cessation.

Bao, R, Liu, G, Li, Z, Ge, Y, Liu, A, Hemodynamic Assessment of Pulmonary Artery on Smokers with 3.0T Phase-contrast MR Imaging: Initial Experience.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14045632.html