Solbee Han, Presenter: Nothing to Disclose

Byung Kwan Park MD, Abstract Co-Author: Nothing to Disclose

Sung Yoon Park, Abstract Co-Author: Nothing to Disclose

Chan Kyo Kim MD, PhD, Abstract Co-Author: Nothing to Disclose

To retrospectively evaluate CT characteristics of adrenal hyperplasia by using adrenal protocol CT

Between January 2004 and November 2012, 14 patients with adrenal hyperplasia and 144 patients with adrenal adenoma had both adrenal protocol CT and surgical confirmation. The adrenal protocol CT consisted of unenhanced, 1-minute, and 15-minute postcontrast images. The lesion size, number, attenuation value, absolute percentage washout (APW), and relative percentage washout (RPW) rates were compared between hyperplasia and adenoma. The mixed model was used for the statistical analysis

Four of 14 patients with adrenal hyperplasia had 3 or more nodules (28.6%), while no patients with adenoma had 3 or more nodules (p< 0.001). Between hyperplasia and adenoma, the mean attenuation value on unenhanced CT image, APW, and RPW rates were 18.8 ± 10.8HU and 13.7 ± 15.6HU (p= 0.106), 73.7 ± 9.3% and 67.3 ± 26.2% (p= 0.187), and 61.2 ± 9.2% and 59.9% ± 23.0% (p= 0.751), respectively. The rates of hyperplasia and adenoma to satisfy CT criteria for adenoma were 100% and 91.7% (p= 1.000).

There is a large overlap quantitatively between adrenal hyperplasia and adenoma on adrenal protocol CT. The multiplicity such as 3 or more nodules may raise the likelihood of hyperplasia

Although adrenal protocol CT has shown excellent diagnostic performance for differentiating adenoma from nonadenoma in the adrenal gland, radiologists now may add adrenal hyperplasia as another differential diagnosis for adenoma because most of hyperplasia also satisfy the quantitative CT criteria of adenoma 

Han, S, Park, B, Park, S, Kim, C, Adrenal Hyperplasia: Analysis by Using Adrenal Protocol Computed Tomography (CT) and Comparison with Adrenal Adenoma.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14045480.html