Cielmar Galeana PhD, Presenter: Nothing to Disclose

Jhonatan Alejandro Vargas MMed, Abstract Co-Author: Nothing to Disclose

Alejandro Garcia Pena MD, Abstract Co-Author: Nothing to Disclose

Oskar Giovanni Lopez Espinoza MD, Abstract Co-Author: Nothing to Disclose

Jorge Vazquez-Lamadrid MD, Abstract Co-Author: Nothing to Disclose

Martha Morelos Guzman, Abstract Co-Author: Nothing to Disclose

OBJETIVE: To determine whether infarct size measured by DE-CMR has predicted involvement in patients with ischemic heart disease.

METHODS: Retrospective study of sixty eight patients who underwent cardiovascular magnetic resonance between September 2004 to September 2008 referrals to suspicion or knowledge of ischemic heart disease. CMR imaging was performed using GE 1.5 T system . Steady state free precession (SSFP) cine MR images were adquired in long axis and short axis orientation. delayed enhacement imaging was performed in the same slice locations using a segmented inversion recovery fast gradient echo sequence. Images were adquired 2-3 minutes to evaluation of the phenomenon non reflow and 10 minutes to assessment of myocardial viability after administration of 0.2 mmol/kg gadolinium contrast. Assessment is made of functional parameters including end diastolic volume (VDF), end systolic volume (ESV), left ventricle ejection fraction ( LVEF) and systolic volume (SV) indexed a body surface area (BSA) presence of fibrosis, their quantification, localization and transmurality.

The average age of the study population was 65.6 years, 12% were in functional class III-IV NYHA, the mortality rate was 16.1%. the 39.7% of the segments presented delay enhacement. The percentage of infarction was significantly higher (21.6% vs. 14.4%) between survivors and the dead (p=0.01). The mayor adverse cardiac events (MACE) were presented in 90% of the group of death compared with 26% de living patients (p=0.001) in relations to survival curve that this declined by a more accelerated during the first week after the ischemic events, and 10 weeks after is slower, with a survival rate de 84% a year since the 2 ½ years of 77% the correlations between infarct size and telesistólico and diastolic volume index left ventricle and left ventricle ejection fraction (LVEF) were statistically significant with a P=<0.001

CONCLUSION: Infarct size measured by delay enhaced cardiovascular magnetic resonance (DE-CMR)has predicted involvement in patients with ischemic heart disease.

Infarct size is related with the incidence of new cardiovascular events. Our hyposthesis is that the bigger the size of the infarct, the outcome of the patient worsens.

Galeana, C, Vargas, J, Garcia Pena, A, Lopez Espinoza, O, Vazquez-Lamadrid, J, Morelos Guzman, M, Infarct Size by Cardiovascular Magnetic Resonance with Technical Delay Enhancement as Factor Prognostic in the Coronary Artery Disease.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14019516.html