Mukta Dilipkumar Agrawal MBBS, MD, Presenter: Nothing to Disclose

Jorge Mario Fuentes MD, Abstract Co-Author: Nothing to Disclose

Manuel Patino MD, Abstract Co-Author: Nothing to Disclose

Pritesh Patel MD, Abstract Co-Author: Nothing to Disclose

Yasir Andrabi MD, MPH, Abstract Co-Author: Nothing to Disclose

Koichi Hayano MD, Abstract Co-Author: Nothing to Disclose

Dushyant V. Sahani MD, Abstract Co-Author: Research Grant, General Electric Company

DECT provides the capability to separate various materials by virtue of differences in their atomic numbers, and therefore attenuation profile, at different energies. This creates opportunities to generate material specific images to derive clinically useful information as outlined below.

• Iodine images allow tissue characterization(iodine content), assess tissue viability, grade liver fibrosis (iodine retention on delayed images), and improve assessment of vascular patency. In cancer patients, improved assessment of local/distant metastasis and quantified iodine can serve as a biomarker of therapeutic response. • Fat images detect and grade hepatic steatosis and characterize fat containing lesions (adenomas, AML) and vascular plaque. • Calcium images quantify bone mineral density, detect intralesion calcium, and characterize vascular plaque and renal stone composition. • Uric acid images diagnose UA stones for appropriate management and visualize urate crystals in the joint, differentiating primary gout vs. pseudo-gout. • Iron images detect and quantify tissue iron and monitor treatment. • Although not currently available, images specific to Gold (inflammation localization), Zinc (β cells in pancreas), Manganese (melanoma) and Copper (Wilson’s) may be generated impacting diagnosis and treatment monitoring.  

http://abstract.rsna.org/uploads/2014/14018961/14018961_44q4.pdf

Agrawal, M, Fuentes, J, Patino, M, Patel, P, Andrabi, Y, Hayano, K, Sahani, D, Material Separation Using Dual-energy CT (DECT): Current and Emerging Applications.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14018961.html