Rajesh Kumar Vartharajaperumal MBBS, DMRD, Presenter: Nothing to Disclose

Pankaj Mehta MD, Abstract Co-Author: Nothing to Disclose

Mathew Cherian MD, Abstract Co-Author: Nothing to Disclose

Prashant Gupta MBBS, MD, Abstract Co-Author: Nothing to Disclose

Tejas Mohan Kalyanpur DMRD, Abstract Co-Author: Nothing to Disclose

Venkatesh Kasi Arunachalam MBBS, DMRD, Abstract Co-Author: Nothing to Disclose

Himani Agarwal MBBS, MD, Abstract Co-Author: Nothing to Disclose

Rahul Rajendra Arkar MBBS, DMRD, DNB, Abstract Co-Author: Nothing to Disclose

Prasen Prakash Shenai MBBS, DMRD, Abstract Co-Author: Nothing to Disclose

(1) To compare the sensitivity of qualitative MRI , Quantitative MRI (T2 relaxometry ) and PET CT in evaluation of patients with mesial temporal lobe epilepsy with video EEG as reference standard. (2) To study the effectiveness of T2 relaxometry in localizing the seizure focus.  

70 consecutive cases with history of complex partial seizure referred for MRI with positive EEG findings were included in the study. The hippocampus was visually assessed for atrophy and objectively with T2 relaxometric value. and combined sensitivity of MRI with T2 Relaxometry and PET CT were compared with EEG findings.  

Hippocampal atrophy was seen in 60% and T2 signal change in 48.6%. Qualitative MRI was concordant with video EEG in 68.65% in lateralization of the epileptogenic focus.Sensitivity of T2 relaxomtery was 85.7%.Hence addition of T2 relaxometry increased the sensitivity of MRI further highlighting the role of T2 relaxometry.Lateralisation by MRI (qualitative and quantitative) and PET agreed with EEG findings in 85.7% and 88.6% respectively.Combined sensitivity of MRI and PET was 94%.

T2 relaxometry significantly improves the lateralization in seizure focus and is comparable to PET however both modalities when combined yield significantly more benefit than each individually.

T2 relaxometry is comparable to PET, doesnt involve ionising radiation and adds significantly inproved sensitivity to the evaluation of MTS

Vartharajaperumal, R, Mehta, P, Cherian, M, Gupta, P, Kalyanpur, T, Kasi Arunachalam, V, Agarwal, H, Arkar, R, Shenai, P, T2 Relaxometry in MTS versus PET and Video EEG.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14018873.html