Mototaka Miyake MD, Presenter: Nothing to Disclose

Yoshiaki Watanabe MD, Abstract Co-Author: Nothing to Disclose

Masakatsu Tsurusaki MD, PhD, Abstract Co-Author: Nothing to Disclose

Kazuro Sugimura MD, PhD, Abstract Co-Author: Research Grant, Toshiba Corporation Research Grant, Koninklijke Philips NV Research Grant, Bayer AG Research Grant, Eisai Co, Ltd Research Grant, DAIICHI SANKYO Group

Yasuaki Arai, Abstract Co-Author: Nothing to Disclose

Neuroblastoma (NB) requires multimodal diagnostic imaging methods including radiography, CT, metaiodobenzylguanidine (MIBG) scintigraphy, and bone scintigraphy, FDG-PET, and MRI. Whole-body MRI (WB-MRI) which enables both local staging and detection of metastatic spread in one approach is useful to minimize radiation exposure during the sequential evaluation of younger patients. This exhibit will show the usefulness and the limitation of WB-MRI for follow-up, re-staging and evaluation of disease response to therapy of NB.

1. Quick Review of the clinical and the multimodal imaging manifestations of neuroblastoma with emphasis on WB-MRI. 2. Introduction of management strategies for follow-up, re-staging and evaluation of disease response to NB. 3. MR imaging techniques to improve quality and consistency in evaluation. The transversal 2D sequential scan including STIR, T2WI, DWI, pre-contrast DIXON and post-contrast DIXON and the high-resolution 3D scan, both of which can be obtained exactly at isocenter, provide seamless images without the boundary artifacts and the distortion. The total scan time of all the sequences is ranging from 45 min to 60 min. 4. Case-based review of recurrence, metastatic disease, treatment response and post-therapeutic surveillance. 5. Pitfalls and limitations of WB-MRI.  

http://abstract.rsna.org/uploads/2014/14018244/14018244_aubk.pdf

Miyake, M, Watanabe, Y, Tsurusaki, M, Sugimura, K, Arai, Y, Whole-body Magnetic Resonance Imaging of Neuroblastoma to Reduce Radiation Exposure: Effectiveness for Follow-up, Re-staging and Evaluation of Disease Response to Therapy.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14018244.html