Padma Priya Manapragada MD, Presenter: Nothing to Disclose

Devaki Shilpa Surasi MD, Abstract Co-Author: Nothing to Disclose

Pradeep G. Bhambhvani MD, Abstract Co-Author: Nothing to Disclose

Jon Albert Baldwin DO, Abstract Co-Author: Nothing to Disclose

Janis Petrik O'Malley MD, Abstract Co-Author: Nothing to Disclose

Samuel E. Almodovar-Reteguis MD, Abstract Co-Author: Nothing to Disclose

 1. Primary bone tumors and metastatic bone involvement  accounts for significant mortality and morbidity. 2. Early detection is difficult, as the majority of patients are asymptomatic. Symptoms include bone pain, deformity, compression of the soft tissues and pathological fractures. 3. Lesions can be lytic, sclerotic or mixed. 4. Bone scan is sensitive routine imaging modality used to identify bone lesions, and SPECT improves the detection. 5. Positron emission tomography (PET) using 18F-fluoride (18F) or 18F-fluorodeoxyglucose (18FDG) also aid in  detecting osseous metastasis. 6. 18F-Fluoride PET/CT is a sensitive and specific modality for detection of bone metastases, and correlation  with non-optimized CT portion increases the sensitivity.  

1. Introduction to nuclear medicine techniques used in the evaluation of osseous lesions 2. Tracer principle behind Tc-99m MDP bone scan (planar and SPECT), F-18 FDG PET and F-18 Fluoride PET, as well as special considerations/limitations per agent will be discussed. 3. Imaging characteristics of lytic, sclerotic , mixed metastases, and metastatic malignancies with osseous metastasis predilection. 4. Differentiating recurrence vs post radiation changes and benign conditions including secondary marrow activation, degenerative disease and incidentalomas will also be described.  

http://abstract.rsna.org/uploads/2014/14018189/14018189_qaop.pdf

Manapragada, P, Surasi, D, Bhambhvani, P, Baldwin, J, O'Malley, J, Almodovar-Reteguis, S, Review of Radioisotope Imaging of Primary and Secondary Malignant Osseous Lesions with F18-FDG PET/CT, F18-Fluoride Bone PET/CT and Tc-99m Bone Scan.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14018189.html