Fatma Fatma Ouamer MD, Presenter: Nothing to Disclose

Anne Bertrand MD, PhD, Abstract Co-Author: Nothing to Disclose

Delphine Leclercq MD, Abstract Co-Author: Nothing to Disclose

Damien Pierre Galanaud MD, PhD, Abstract Co-Author: Research Consultant, Olea Medical

Peggy Bienvenot MD, Abstract Co-Author: Nothing to Disclose

Sophie Beranger-Gibert, Abstract Co-Author: Nothing to Disclose

Didier Dormont MD, Abstract Co-Author: Nothing to Disclose

To recognize an abnormal enhancement of perivascular spaces on MR imaging. To list the different diagnoses related to perivascular space enhancement on MR imaging. To characterize the specific MR appearance of each of these diagnoses.  

 Anatomical and neuropathological considerations Imaging findings and key points Perivascular space enhancement can be recognized as punctate and linear enhancement located along the perforating arteries: within the pons, the basal ganglia and the centrum semi ovale. Possible diagnoses included: Inflammation:Neurosarcoidosis : granulomatous leptomeningitis with predilection for the basal meninges and basal midline structures .Lymphomatoid granulomatosis : multifocal angiocentric lymphoreticular proliferative and granulomatous lesions  perivascular space enhancements are associated with patchy hyperintense lesions on T2WI  Erdheim-Chester disease causing osteosclerosis of the facial bone, orbital masses and periarterial masses  C.L.I.P.P.E.R.S  Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids.CNS vasculitis,angiitis granulomatosis.Tumors: CNS lymphoma and glioma.Infections:PML-IRIS and Cryptococcal meningitis–IRIS in the setting of HIV-related immunosuppression :  perivascular spaces enhancement suggest inflammatory response,a hallmark of CNS-IRIS  

http://abstract.rsna.org/uploads/2014/14018113/14018113_i2x3.pdf

Ouamer, F, Bertrand, A, Leclercq, D, Galanaud, D, Bienvenot, P, Beranger-Gibert, S, Dormont, D, Perivascular Space Enhancement: Key Points for Diagnosis.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14018113.html