1. To review the differential diagnosis of symmetric bilateral thalamic diseases.
2. To illustrate MRI features of different thalamic pathologies, and review the associated extrathalamic findings and clinical history that aid in differentiation.
Pathophysiology, MRI characteristics, images and clinical course of various pathologies resulting in abnormal bilateral thalamic MRI abnormalities. The differential diagnosis includes vascular, infectious, metabolic and neoplastic entities including but not limited to:
Creutzfeldt-Jakob disease(CJD)
Vasculitis
Hypoxic ischemic encephalopathy(HIE)
Hypertensive encephalopathy, PRES
Osmotic demyelination
Wilson's disease
Wernicke's encephalopathy
Viral encephalitis West Nile/Japanese/rabies/E. Equine
Fabry disease
Leigh syndrome
Fahr disease
Venous occlusion/deep vein thrombosis
Arterial ischemia: Artery of Percheron occlusion
Bilateral thalamic glioma
Gharavi, M,
Markovic, M,
Tips and Tricks for Narrowing the Differential Diagnosis of Bilateral Abnormal Thalamic Signal Intensity on MRI. Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL.
http://archive.rsna.org/2014/14018068.html