Haq Wajid DO, Presenter: Nothing to Disclose

Ram Kishore Reddy Gurajala MBBS, FRCR, Abstract Co-Author: Nothing to Disclose

Dianna Yu Ning Yang DO, Abstract Co-Author: Nothing to Disclose

Shetal N. Shah MD, Abstract Co-Author: Nothing to Disclose

Amanjit Singh Gill MD, Abstract Co-Author: Nothing to Disclose

Karunakaravel Karuppasamy MBBS, FRCR, Abstract Co-Author: Nothing to Disclose

The goal is • To review multiple criteria that can be used to evaluate response to embolotherapy in hepatocellular carcinoma (HCC)  • To highlight key differences between these criteria  • To demonstrate varying impact these criteria can have  

A. Background: An overview of tumor treatment response criteria by World Health Organization (WHO), the European Association for the Study of the Liver (EASL), and Response Evaluation Criteria in Solid Tumors - RECIST version 1.1 and modified RECIST (mRECIST) is presented. B. Highlight major differences: a. WHO and RECIST 1.0 and 1.1 are based on entire tumor size b. EASL and mRECIST are based only on viable residual tumor c. WHO and EASL are based on bi-dimensional measurements d. RECIST 1.1 and mRECIST are based on greatest uni-dimensional measurement   C. Brief review on prognostic correlation between these criteria and HCC   D. EASL and mRECIST a. Special significance in HCC b. Example cases: Like the one case shown in the images, based on the criteria used, residual tumor size and description of treatment response can vary.   E. SUMMARY: With the prediction of viability depending on imaging, a consistent methodology adopted throughout the follow-up period will aid in better management of HCC.  

http://abstract.rsna.org/uploads/2014/14017973/14017973_ueub.pdf

Wajid, H, Gurajala, R, Yang, D, Shah, S, Gill, A, Karuppasamy, K, WHO, EASL, RECIST 1.1 and mRECIST Criteria: A Case-based Pictorial Illustration on Key Differences in Radiologic Assessment of Response after Embolotherapy in Hepatocellular Carcinoma.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14017973.html