Pouya Ziai MD, Presenter: Nothing to Disclose

Mohammadreza Hayeri MD, Abstract Co-Author: Nothing to Disclose

Oleg Teytelboym MD, Abstract Co-Author: Nothing to Disclose

1. Become familiar with quantitating FDG uptake on PET-CT, including SUV mean, max, peak, whole body, and lean body. 2. Understand factors that can influence SUV measurement reproducibility. 3. Understand SUV normalization approaches. 4. Become familiar with best practices in improving SUV measurement accuracy and minimizing the confounding factors.  

Introduction Definitions PET-CT impact on modern oncologic practice Utilization of PET-CT for detection, staging, and treatment response assessment Methods for 18F-FDG PET data analysis Qualitative  Semiquantitative → standardized uptake value (SUV) Quantitative  Reporting SUV SUVmax SUVmean SUVpeak Confounding factors in measuring SUV Biologic factors Weight composition  Body size calculation Blood glucose level Postinjection uptake time Respiratory motion Technologic factors Scanner variability Reconstruction parameter changes Calibration error between scanner and dose calibrator Timing mismatch between scanner and dose calibrator Use of contrast material for PET/CT Interobserver variability Standardization of quantitative 18F- FDG PET studies SUV normalization Normalization to weight Normalization to selected reference tissue Normalization to plasma glucose  

http://abstract.rsna.org/uploads/2014/14017579/14017579_n8a4.pdf

Ziai, P, Hayeri, M, Teytelboym, O, SUV: Everything You Wanted to Know but Afraid to Ask!.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14017579.html