Yan Liang MMed, Abstract Co-Author: Nothing to Disclose

Zhiren Chen MD, Presenter: Nothing to Disclose

Chuang Yi, Abstract Co-Author: Research Grant, General Electric Company

Bin 00617875. Li, Abstract Co-Author: Nothing to Disclose

Dongbin Shi, Abstract Co-Author: Nothing to Disclose

Yongfang Yin, Abstract Co-Author: Nothing to Disclose

To compare vascular enhancement between a low-kilovoltage renal artery CT angiography (CTA) protocol using a low-concentration iodixanol(270mgI/mL) and routine 120kV protocol with high-concentration iohexol(350 mg I/mL) contrast medium .

30 patients (body mass index, ≤ 23 kg/m(2)) with suspected renal artery stenosis underwent renal artery CTA with a 64-MDCT scanner using a tube voltage of 80 kV. Patients were received 70 mL of iodixanol (270 mg I/mL) injected at a rate of 5 mL/s. And 32 patients(BMI>23 kg/m(2)) were administered an equal volume of iomeprol (350 mg I/mL) at a delevery rate of 5 mL/s. Images of 80kVp group were post-processed with adaptive statistical iterative algorithm(50%ASiR).For both groups, the CT values and SD values of aorta, subcutaneous fat and the erector spine muscle were measured, and the averaged SD value was calculated as the image noise. The signal-noise-ratio (SNR) and contrast-noise-ratio (CNR) for aorta, artery and left renal artery and right renal artery were calculated respectively.

For low-kVwith ASiR group, the enhancement of aorta , artery and left renal artery and right renal artery (223.4±23.8, 261.0±32.2 and 267.2±31.0) were compatible with those in routine120 kV group(271.3±30.4, 223.9±25.6 and 256.3±32.1)(each p>0.05). The CNR of aorta , artery and left renal artery and right renal artery (32.1±7.8, 32.4±6.7 and 31.8±4.7) in low-kVCTA group was slightly higher than those in conventional CTA group(28.6±6.4,29.9±6.1 and 29.3±9.4)(each p>0.05). Enhancement homogeneity was good with both contrast agents, with no statistically significant difference between them (p>0.05)

In 80-kV renal artery CTA of lean patients, higher intravascular enhancement can be achieved with iodixanol(270 mg I/mL),with good vessel conspicuity down to the sub-segmental level.

In patients of BMI<=23 with reduced contrast medium, low-kV (80kV) renal artery CTA provides compatible image quality with conventional (120kV) renal artery CTA.

Liang, Y, Chen, Z, Yi, C, Li, B, Shi, D, Yin, Y, BMI-based Tube Kilovolt Selection Combined with Iodixanol (270 mg I/mL) and Iohexol (350 mg I/mL) in Achieving Coherent Vascular Enhancement in Renal Artery CT Angiography.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14017495.html