Yi Jiang, Presenter: Nothing to Disclose

Wenya Liu, Abstract Co-Author: Nothing to Disclose

Jingjing Wan MD, Abstract Co-Author: Nothing to Disclose

The aim of this study is to discuss whether the weight tailored contrast media injection plan could result in same or better image quality in abdominal dual-phase CT scan compare with conventional injection plan with constant infusion parameters.

Abdominal dual-phase CT was performed on 90 patients(48 female and 42 male; average age, 47±12 years) which were prospectively randomized into two groups according to the rate and dose of contrast media injection: weight-adjusted iodine-dose protocol and constant iodine-dose protocol(3.5mL/s and 80mL). Both two groups adopt same concentration of contrast media(320 mgI/mL).Moreover,3 subgroups were divided in each group in accordance with the weight grade(under 55, 55~70, 0ver 70). Quantitative analysis: the CT values of liver, kidney, celiac trunk and portal vein were measured during the artery phase(AP) and portal vein phase(PVP) in each group. Qualitative analysis: Image quality was evaluated by two experienced doctors. And the results included good, common and bad.

Although all target tissues with sufficient attenuation measured in group weight-adjusted iodine-dose was lower than that of group constant iodine-dose, there were no significant difference among the measured attenuation of liver, kidney, celiac trunk and portal vein between weight-adjusted iodine-dose protocol and protocol during the AP and PVP(all p>0.05),while those in subgroups were approximate (all P>0.05).Image quality of group weight-adjusted iodine-dose wasn’t fundamentally different from group constant iodine-dose. Image quality of subgroup with weight under 55 was better than that of other subgroups under the weight-adjusted iodine-dose protocol, either large or small vessels were manifested clearly without artifact.

 Based on weight-tailored, infusion protocols using concentrations of 320, mgI/mL can achieve approximate attenuation levels compare with constant iodine-dose protocol.

Abdominal dual-phase CT scan based on  weight tailored contrast media injection plan can reduce the dose and rate of contrast medium without affecting the quality of imaging, further reducing the risk of side effect of contrast medium for patient.

Jiang, Y, Liu, W, Wan, J, The Clinical Application of Optimization Contrast Medium Infusion Protocol Tailored to Body Weight in Abdominal Dual-phase CT Scan.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14017456.html