Laryngeal dysfunction (LD) characterized by the inappropriate closure of vocal cords during breathing is often misdiagnosed as steroid-resistant asthma. 320-slice CT larynx permits real-time viewing of laryngeal movement and may replace laryngoscopy in the LD diagnosis. An analysis algorithm has been established for quantification of LD based on a Real Time ratio of vocal cord lateral diameter to tracheal diameter (RATIOS). Manual measurements have been tediously performed at 0.35 seconds intervals of the breathing cycle and can be subject to measurement error. The aim of this exhibit is to demonstrate the efficacy of a new computing automated measurement software programme (CAMSP) installed in the workstation that aids LD diagnosis.
1. 154 adult patients with asthmatic symptoms and 46 age-matched normal individuals were recruited for 4-D dynamic CT of larynx.
2. RATIOS were obtained over the breathing cycle both manually and by CAMSP that automatically defines a centre line through the airway lumen and obtains appropriate linear dimensions and area. Bland-Altman analysis confirmed the concordance and agreement between the CAMSP and manual results. Average time required for CAMSP is 72% less compared to manual.
3. CAMSP gives more objective and reproducible results that aids the prompt diagnosis of LD.
Lau, K,
Hislop-Jambrich, J,
4-dimensional Computerised Tomography of Larynx: Efficacy of an Automated Software Programs for Imaging and Diagnosis of Laryngeal Dysfunction. Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL.
http://archive.rsna.org/2014/14017265.html
