Abstract Archives of the RSNA, 2014
PDE011-b
F18-FDG PET CT Characterization and Histopathological Correlation of Non –CNS (Central Nervous System) Neoplasms in the Pediatric Population
Education Exhibits
Presented in 2014
Sajeev Rajan Ezhapilli MBBS, Presenter: Nothing to Disclose
Mary McGrath MD, Abstract Co-Author: Nothing to Disclose
Michele Lisi MD, Abstract Co-Author: Nothing to Disclose
Andrij Roman Wojtowycz MD, Abstract Co-Author: Nothing to Disclose
Nelli Lakis MD, Abstract Co-Author: Nothing to Disclose
David H.I. Feiglin MD, Abstract Co-Author: Nothing to Disclose
F18-FDG PETCT allows detection of non CNS malignant tumors in the pediatric population with great accuracy and helps in initial staging and treatment planning of tumors.
F18-FDG PET-CT outscores conventional imaging in detection of residual/recurrent tumor as well as lymph node and distant metastases by its ability to whole body at a single time to detect viable tumor , thus determining treatment response.
This exhibit reviews a spectrum of non CNS childhood malignancies encountered on F18-FDG PET CT examinations at our institution such as lymphoma, soft-tissue and malignant bone tumors, neuroendocrine tumors and melanoma. F18-FDG PET CT offers detection of unknown primary tumor site, malignancy within lymph nodes which do not qualify as abnormal by size criteria on CT as well as viability within solid tumors like sarcoma which do not demonstrate uniform size reduction after chemotherapy. Furthermore, this exhibit includes histopathological correlations supplementing PET-CT findings, thus improving accuracy of diagnosis, preoperative interventions, treatment and follow-up. Occasionally, pathologies like inflammation and brown fat uptake can mimic malignancy in pediatric patients. Additional drawbacks include limited detection of lesions smaller than 5 mm, well-differentiated tumors and tumors with low metabolic activity.
http://abstract.rsna.org/uploads/2014/14016641/14016641_brpp.pdf
Ezhapilli, S,
McGrath, M,
Lisi, M,
Wojtowycz, A,
Lakis, N,
Feiglin, D,
F18-FDG PET CT Characterization and Histopathological Correlation of Non –CNS (Central Nervous System) Neoplasms in the Pediatric Population. Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL.
http://archive.rsna.org/2014/14016641.html