Arbab Zafar Iqbal MD, Presenter: Nothing to Disclose

Thomas Lostracco MD, Abstract Co-Author: Nothing to Disclose

Ali Haikal Hussain MD, FRCR, Abstract Co-Author: Nothing to Disclose

Provide a thorough overview of progressive multifocal leukoencephalopathy. Discuss PML and its specific risk factors including new immune modulating agents like Natalizumab for treatment of MS. Stress the importance of early detection of PML for treatment. Review the imaging appearance of PML in both conventional and advanced imaging modalities including DTI, perfusion, and spectroscopy  to help distinguish PML from other related conditions such as PML IRIS and demyelination. After the review, show a series of cases which highlight the most important teaching points.

Overview of PML. Discuss the reemergence of PML secondary to treatment of MS. Discuss the treatment of PML. Overview and discussion of the radiological appearance of PML on both conventional and advanced imaging modalities such as DTI, perfusion, and spectroscopy. Review the key imaging findings which distinguish PML from other related conditions using cases to help illustrate the differences. 

http://abstract.rsna.org/uploads/2014/14016630/14016630_rzcf.pdf

Iqbal, A, Lostracco, T, Hussain, A, Progressive Multifocal Leukoencephalopathy: A Reemerging Beast.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14016630.html