Nidhin Hafeez MBBS, Presenter: Nothing to Disclose

Kanchan Gupta MD, Abstract Co-Author: Nothing to Disclose

Sunitha P Kumaran MBBS, MD, Abstract Co-Author: Nothing to Disclose

Sanjaya Viswamitra MD, Abstract Co-Author: Nothing to Disclose

Nandita Ghosal MD, Abstract Co-Author: Nothing to Disclose

•MRI -non-invasive, accurate modality to diagnose and assess craniopharyngioma -differentiates histological subtypes of craniopharyngioma •Helps in deciding surgical approach •Prefered modality for post-op follow up

Retrospective study of MRI of 102 histologically proven craniophayngiomas[Feb'10-Mar'12] revealed spectrum of imaging and histopathological findings, 89 adamantinomatous,12 papillary and 1 melanotic -rare variant  noted. Aged 4-60yrs:Mean±SD:25±18. Adamantinomatous were large,lobulated,predominantly cystic with solid components,calcification,infiltrative,hyperintense T1,T2,FLAIR, peripheral/hetero/nodular enhancement;ADC(2.1–3.4x10-3mm/s),poor prognosisand recurrence.Fluid levels,bilateral ICAencasement,optic chiasmatic and hypothalamic compression seen.MRS  lipid peak in 6 adamantinomatous with histopathologicaly proven cholesterol clefts,total tumor excision done.Papillary were well defined,noninfiltrative,predominantly solid, T1hypo, T2hetero, mixed enhancing with ADC(1.1-3.4x10-3mm/s),no recurrence and good prognosis.This  exhibit illustrates spectrum of MRI features of craniopharyngioma which helps in correct radiological diagnosis of histological subtypes.Knowledge of clinical, MR imaging and histopathologic spectrum aids in differentiation of this neoplasm since prognosis and therapeutic options differ.  

http://abstract.rsna.org/uploads/2014/14016625/14016625_3ucw.pdf

Hafeez, N, Gupta, K, Kumaran, S, Viswamitra, S, Ghosal, N, Common and Uncommon MR Imaging Spectrum in Craniopharyngioma: Radiopathologic Correlation.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14016625.html