Ali Salavati MD, MPH, Presenter: Nothing to Disclose

Sina Houshmand MD, Abstract Co-Author: Nothing to Disclose

Thomas J. Werner, Abstract Co-Author: Nothing to Disclose

Benjapa Khiewvan, Abstract Co-Author: Nothing to Disclose

Saeid Gholami MD, Abstract Co-Author: Nothing to Disclose

Abass Alavi MD, Abstract Co-Author: Nothing to Disclose

To review the advances in molecular imaging of atherosclerosis and vessel wall inflammation using FDG-PET/CT and sodium 18F Fluoride -PET/CT. To review the impact of different methodological factors on vessel wall imaging and quantification of 18F-FDG and sodium 18F Fluoride PET/CT scans. 

18F-FDG PET/CT is a noninvasive, accurate and reproducible imaging modality that can identify and quantify inflammatory processes and prognosticate the risk for acute cardiovascular disease. Imaging vascular calcification by sodium 18F fluoride PET/CT can possibly improve cardiovascular risk stratification by detecting calcification in vascular wall and also differentiate active from indolent calcification. In this review, we will discuss advances and improvements in application of FDG-PET/CT and sodium 18F Fluoride PET/CT in atherosclerotic plaque inflammation and effects of methodological factors on accurate quantification of vessel wall inflammation. 1) FDG-PET/CT 2) Sodium 18F Fluoride 3) Methodological factors i. Delayed time point ii. Pre-scan variables iii. FDG Uptake parameters
 a. Qualitative b. Semi-quantitative c. Quantitative  

http://abstract.rsna.org/uploads/2014/14016082/14016082_q1jx.pdf

Salavati, A, Houshmand, S, Werner, T, Khiewvan, B, Gholami, S, Alavi, A, The Emerging Role of 18F-FDG and Sodium 18F Fluoride PET/CT in the Assessment of Atherosclerotic Plaques: An Update  [ MI Scavenger Hunt! ].  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14016082.html