Vera Lucia Nunes Aguillar MD, Presenter: Nothing to Disclose

Vera Christina Camargo de Siqueira Ferreira MD, Abstract Co-Author: Nothing to Disclose

Erica Endo MD, Abstract Co-Author: Nothing to Disclose

Carla Basso Dequi MD, Abstract Co-Author: Nothing to Disclose

Daniela Gregolin Giannotti MD, Abstract Co-Author: Nothing to Disclose

Giovanni Guido Cerri MD, PhD, Abstract Co-Author: Nothing to Disclose

to determine performance of whole breast ultrassonography (US) in women who underwent additional breast US during the first year of implementation of breast tomosynthesis (digital mammography - DM - plus tomosynthesis (BT), in a screening population

Prospective study, including 1034 consecutive women, age 35-85 year-old, who underwent screening tomosynthesis for the first time: 2 views DM + 2 views BT of each breast, with sequential reading and consensus arbitration and, subsequently, had physician performed handheld whole breast US, from september/2011 through august/2012.

Twenty - six cases were classified as BI-RADS category 4 or 5 by screening BT and 24 were submitted to biopsy with 12 cancers found (4 DCIS and 8 invasive). In subsequent screening US, 09 lesions sere classified as BIRADS category 4 , all submitted to FNA of biopsy and one cancer was found: lobular invasive carcinoma, HG1, NH 1 , 6 mm, LS negative. Of 13 cancers detected in this screening population, with BT and additional US, 12 could be seen by tomosynthesis (4 DCIS and 8 invasive), while only 7 were detected by US (all invasive). Cancer detection rate was 1,16% (12/1034) with breast tomosynthesis and increased to 1,26% (13/1034), with additional US. Adding US to BT increase the number of biopsies from 26 to 35. PPV3 for US only lesion detection was 1,1 (1/9) compared to 50% for lesions detected by tomossynthesis

Adding physician-performed handheld US to breast tomosynthesis had a little impact in cancer detection rate and a low overall PPV. Further clinical studies are needed with a large number of women, especially with dense breasts.

Screening breast ultrasound

Aguillar, V, Ferreira, V, Endo, E, Dequi, C, Giannotti, D, Cerri, G, Whole Breast US after Screening Breast Tomosynthesis: Initial Experience.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14016080.html