J. Bruce Kneeland MD, Presenter: Nothing to Disclose

Kevin D'Aquilla BS, Abstract Co-Author: Nothing to Disclose

Vishal Saxena MD, Abstract Co-Author: Nothing to Disclose

Joshua Gordon MD, Abstract Co-Author: Nothing to Disclose

Anup Singh, Abstract Co-Author: Nothing to Disclose

Hari Hariharan PhD, Abstract Co-Author: Nothing to Disclose

Brian Sennett MD, Abstract Co-Author: Nothing to Disclose

Ravinder Reddy PhD, Abstract Co-Author: Nothing to Disclose

To detect injury to glenohumeral articular cartilage following subacute dislocation in the absence of morphologic defects (GLAD) using T1ρ MRI

12 subjects ages 18-40 underwent MRI at 3T using both conventional (FSE) sequences and T1ρ MRI. T1ρ MRI was performed using an aniostropic 3D gradient echo sequence acquired in the coronal plane with 256x256 acquisition matrix and 8 slices with 3.6 mm slice thickness. The sequence was repeated using spin lock pulses of 0-40 msec duration (in 10 msec increments) to permit the pointwise calculation of T1ρ. Humeral and glenoid cartilage were manually segmented and displayed in color-coded images with color dependent on quantitative T1ρ calculations. Comparison of T1ρ values of the humeral and glenoid cartilage in these patients was made to 5 asymptomatic subjects.

In comparison to the values in the asymptomatic subjects, the mean T1ρ values of the humeral articular cartilage in patients with subacute dislocations were increased by more than 1 standard deviation, while mean T1ρ values of cartilage in the glenoid were increased by more than 2 standard deviations. These indicate statistically significant increases in T1ρ in these patients.

T1ρ maps in patients with subacute shoulder dislocation demonstrated a diffuse increase in the value of both the humeral and articular cartilage that was both statistically significant and that indicated on the basis of prior work with cartilage degeneration a significant degneration of the proteoglycan macromolecular matrix

Extent and severity of cartilage injury can impact rehabilitation and other conservative means of management following shoulder dislocation

Kneeland, J, D'Aquilla, K, Saxena, V, Gordon, J, Singh, A, Hariharan, H, Sennett, B, Reddy, R, Use of T1ρ MRI For Assessment of Glenohumeral Joint Cartilage Injury Following Subacute Shoulder Dislocation.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14015506.html