Emmanuel C. Obusez MD, Presenter: Nothing to Disclose

Shetal N. Shah MD, Abstract Co-Author: Nothing to Disclose

Bandar Osaid Safar MD, Abstract Co-Author: Nothing to Disclose

Unni K. Udayasankar MD, FRCR, Abstract Co-Author: Nothing to Disclose

Guiyun Wu MD, Abstract Co-Author: Nothing to Disclose

Stephen Edward Jones MD, PhD, Abstract Co-Author: Nothing to Disclose

1. Emphasize the clinical significance of simultaneous PET/MRI in the improving the detection of epilepsy foci. 2. Illustrate with simultaneous fused-FDG-PET/MRI findings of epileptic foci.  

1. Briefly review the role of MRI in epilepsy a. Discuss current MRI imaging findings and limitations in the evaluation of epilepsy foci. Limited to focal cortical dysplasia, meso temporal sclerosis, polymicrogyria and heterotopia. 2. Describe current technical advances in PET/MRI and its use in neuroimaging. 3. Discuss the clinical utility of fused-FDG-PET/MRI for evaluation of epilepsy foci and advantages over structural MRI.  Fused-PET/MRI is a modality that offers superior diagnostic advantages. Patients with medically refractory epilepsy may be candidates for surgery. This cohort of patients may have a positive surgical outcome with the identification of epileptic foci on MRI. However, some patients show indeterminate or no evidence of structural abnormality on MRI. In these subset of patients, fused-FDG-PET/MRI is increasing being used as a tool to enhance pre-surgical identification of epileptic foci. Learn the clinical utility of fused-FDG-PET/MRI and its advantages - such as new regions of hypometabolic epileptic foci not seen on MRI and ability to delineate anatomic boundaries of hypometabolism not identified on PET.

http://abstract.rsna.org/uploads/2014/14015341/14015341_wrk3.pdf

Obusez, E, Shah, S, Safar, B, Udayasankar, U, Wu, G, Jones, S, Simultaneous Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI): Clinical Advances and Implications in Neuroimaging of Epilepsy.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14015341.html