Mayumi Takeuchi MD, PhD, Presenter: Nothing to Disclose

Kenji Matsuzaki MD, PhD, Abstract Co-Author: Nothing to Disclose

Masafumi Harada MD, PhD, Abstract Co-Author: Nothing to Disclose

1. Normal gynecologic organs may show dynamic morphologic changes due to various physiologic states and may mimic pathologies, whereas imaging manifestations of benign gynecologic pathologies may also be influenced by various physiologic states. Radiologists should check physiologic states of patients before interpreting the images. 2. Decidualization of ectopic endometrium in endometrioma or adenomyosis, usually associated with pregnancy or occasionally with exogenous hormonal stimulation, may mimic malignancy such as ovarian cancer or endometrial stromal sarcoma of the uterus. DWI with ADC measurement may be helpful in distinguishing hypercellular malignant tumors with decreased ADC and edematous decidualized lesions with increased ADC. 3. Changes in MR appearance of normal gynecologic organs and benign lesions may be the first manifestation of exo-/ endogenous hormonal abnormality.

Physiologic changes during menstrual cycle: Endometrioma /Lung endometriosis Pregnancy-related changes: Decidualized endometrioma; adenomyosis /Red degeneration of leiomyoma /Torsion of ovarian tumors Exo-/ Endogenous hormone-related changes: -Response to the therapy /Menopause: Adenomyosis/ Leiomyoma -Stepwise carcinogenesis of endometrium /hyperplasia: Tamoxifen/ Functioning ovarian tumors/ PCO Infection and inflammatory changes

http://abstract.rsna.org/uploads/2014/14013917/14013917_vyya.pdf

Takeuchi, M, Matsuzaki, K, Harada, M, MR Manifestations of Various Physiologic Environmental Changes in the Benign Gynecologic Pathologies.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14013917.html