Mayumi Takeuchi MD, PhD, Presenter: Nothing to Disclose

Kenji Matsuzaki MD, PhD, Abstract Co-Author: Nothing to Disclose

Masafumi Harada MD, PhD, Abstract Co-Author: Nothing to Disclose

1. The endometrial cavity may demonstrate various imaging manifestations: reactive, inflammatory, and benign and malignant tumors. 3D DCE-MRI is useful for characterizing lesions by evaluating vascularity, volume of the extra-cellular space, and presence of degenerated or necrotic areas. 2. DCE-MRI may be helpful for the diagnosis of high grade malignancies with angiogenesis such as type II endometrial cancers, however, some low grade tumors or benign lesions may occasionally show hypervascularity. 3. Peritumoral CE may reveal the attachment site of tumors and be helpful in evaluating the tumor extent, however, may occasionally cause overestimation of myometrial invasion due to the disruption of SEE. 4. 3D DCE-MRI can clearly demonstrate small hypervascular foci of gestational lesions within clots or necrotic tissue in the endometrial cavity.

Imaging techniques of 3D DCE-MRI Causes of hypervascularity: Tumor angiogenesis; peritumoral CE; gestational reaction Malignant tumors: - High grade: Type II cancer /Carcinosarcoma - Low grade: Type I cancer with squamous differentiation - Secondary involvement: Metastasis /Lymphoma Benign lesions: - Gestational lesions: Retained products of conception /Placental polyp /Gestational trophoblastic disease - Myometrial origin: Submucosal leiomyoma

http://abstract.rsna.org/uploads/2014/14013909/14013909_oc1m.pdf

Takeuchi, M, Matsuzaki, K, Harada, M, Hypervascular Lesions of the Endometrial Cavity: The Diagnostic Impact of 3D DCE-MRI.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14013909.html