Venkata S. Katabathina MD, Presenter: Nothing to Disclose

Erin Flaherty MD, Abstract Co-Author: Nothing to Disclose

Nicole Riddle MD, Abstract Co-Author: Nothing to Disclose

Anil Kumar Dasyam MD, Abstract Co-Author: Nothing to Disclose

Narayan Lath, Abstract Co-Author: Nothing to Disclose

Srinivasa R. Prasad MD, Abstract Co-Author: Nothing to Disclose

Review anatomy & embryology of biliary tract with emphasis on peribiliary glands List select inflammatory and neoplastic diseases of biliary tract that have pancreatic counterparts Discuss evolving concepts regarding pathogenesis along with molecular & cytogenetic abnormalities Describe CT/MRI findings & role of imaging in diagnosis & management  

Introduction Anatomy & development of biliary tract Inflammatory diseases: IgG4 sclerosing cholangitis-autoimmune pancreatitis; primary sclerosing cholangitis-idiopathic duct centric chronic pancreatitis Neoplasms: Cholangiocarcinoma-pancreatic adenocarcinoma; Intraductal papillary mucinous neoplasm of bile duct (IPMN-B)- IPMN of pancreas (IPMN-P); Biliary mucinous cystic neoplasm (MCN) and IPMN-B with cystic change-pancreatic MCN & IPMN-P with cystic changes Recent advances in pathogenesis, molecular biology & cytogenetics Conclusion Biliary tract & pancreas develop from endoderm, peribiliary glands demonstrate remnants of pancreatic tissue. Select biliary pathologies show similar pathogenesis & imaging findings to their pancreatic counterparts; this has lead to proposal of a new disease concept ‘biliary diseases with pancreatic counterparts’. This unified concept will assist in understanding pathogenesis of pancreatico-biliary diseases & developing novel therapeutic strategies.  

http://abstract.rsna.org/uploads/2014/14013892/14013892_fyol.pdf

Katabathina, V, Flaherty, E, Riddle, N, Dasyam, A, Lath, N, Prasad, S, “Biliary Diseases with Pancreatic Counterparts”: Evolving Concepts in Pathogenesis and Cross-sectional Imaging Findings.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14013892.html