Myrna Cobos Barco Godoy MD, PhD, Presenter: Nothing to Disclose

Stephen G. Swisher MD, Abstract Co-Author: Consultant, GlaxoSmithKline plc

John V Heymach MD,PhD, Abstract Co-Author: Nothing to Disclose

Junya Fujimoto MD, PhD, Abstract Co-Author: Nothing to Disclose

Ignacio Wistuba MD, Abstract Co-Author: Nothing to Disclose

Jeremy J. Erasmus MD, Abstract Co-Author: Nothing to Disclose

1. Subsolid nodule includes pure ground-glass nodules (GGNs) and part-solid nodules (PSNs). 2. Strong correlation has been demonstrated between the histologic findings of lung adenocarcinoma with lepidic growth pattern and the CT appearance of persistent subsolid nodules. 3. Serial CT imaging has demonstrated stepwise progression of GGNs in a subset of patients, characterized by increase in size and density, as well as development of a solid component. 4. Given the slow growth rate of GGNs, standardized guidelines with long-term (≥ 3 years) CT follow-up have been proposed using low-dose CT technique. 5. Given the correlation of invasive tumor with the solid component in persistent PSNs, surgical resection should be considered. 6. Radiologists must be familiar with current guidelines for management of solitary and multiple subsolid nodules.  

1. CT-pathologic correlation of the IASLC/ATS/ERS lung adenocarcinoma classification and its clinical significance. 2. Case-based review of differential diagnosis of subsolid nodule. 3. Case-based review of isolated subsolid lung nodules management. 4. Case-based review of management of multiple subsolid lung nodules. 5. Case-based review of CT/genomic biomarker correlation.  

http://abstract.rsna.org/uploads/2014/14013629/14013629_1kst.pdf

Godoy, M, Swisher, S, Heymach, J, Fujimoto, J, Wistuba, I, Erasmus, J, Managing Subsolid Lung Nodules: A Case-Based Approach.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14013629.html