Young Han Lee MD, Presenter: Nothing to Disclose

Dosik Hwang, Abstract Co-Author: Nothing to Disclose

Jaemoon Yang, Abstract Co-Author: Nothing to Disclose

Dan Heo, Abstract Co-Author: Nothing to Disclose

Bonjune Kim, Abstract Co-Author: Nothing to Disclose

Jin-Suck Suh MD, Abstract Co-Author: Nothing to Disclose

The proposed triple fusion method using CT, PET, and MR can improve the delineation of the cortical bone and soft tissue. This triple fusion method might be utilized in pre-procedure planning such as CT-guided procedure.

To evaluate the usefulness of triple fusion of MR, PET, and CT images based on Bone-edge specific maximum overlapping (BESMO) for CT-guided biopsy of MR- or PET-detected lesions.

The protocol of this retrospective review was approved by the institutional review board. The MR, PET, and CT images were retrieved from PACS server. The fusion images were retrospectively reconstructed using dedicated software written in Matlab (Mathworks). After acquiring DICOM images from PACS server, bone mask from CT and bone mask from MR were obtained to co-registration of the images. The bone contours from the CT and MR images were used as picking points to fuse the images. Co-registration scheme of Bone-edge specific maximum overlapping (BESMO) algorithm was verified to be geometrically practical. In order to determine the detection rates, 12 metastatic lesions from 5 patients were evaluated. All MR, PET, and CT images and various fusion images were retrospectively evaluated in terms of visualization of metastatic lesions.

Triple image fusion software was implemented at real-time workstation based on automatic co-registration. The MR, PET, and CT images can be fused across modalities of MR/PET, MR/CT, PET/CT, and MR/CT/PET by applying transparent layer. Each modality can be seen as a layer, and the visualization weighting factors can be controlled in terms of transparency. We evaluated the metastatic lesions on various fusion images and each modality images presenting metastasis, and these images showed no significant difference for each modality in statistics. Additionally, triple fusion images could visualize bone cortical lesion as well as soft tissue lesions.

Lee, Y, Hwang, D, Yang, J, Heo, D, Kim, B, Suh, J, Detection of Metastatic Lesion with Triple Fusion of MR, PET, and CT Images based on Bone-edge Specific Maximum Overlapping (BESMO): A Retrospective Study of Patients with Metastasis Clinical Application of Triple Fusion of MR, PET, and CT Images Base.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14013344.html