John Webster Gilbert MD, Presenter: Nothing to Disclose

Atul Bhanudas Shinagare MD, Abstract Co-Author: Nothing to Disclose

Jyothi Priya Jagannathan MD, Abstract Co-Author: Nothing to Disclose

Brian M Wolpin MD, Abstract Co-Author: Nothing to Disclose

Nikhil H. Ramaiya MD, Abstract Co-Author: Nothing to Disclose

Michael Hayden Rosenthal MD, PhD, Abstract Co-Author: Nothing to Disclose

- About 70% of patients with pancreatic cancer present with locally advanced or metastatic disease, and another 5-10% have borderline resectable cancer. - These three classes of pancreatic cancer undergo distinct treatments and demand different areas of vigilance on the part of the radiologist. - Neoadjuvant therapy for borderline resectable tumors is performed with goal of resection and potential cure; locally advanced and metastatic tumors are treated for local control and palliation.  

- Review of normal anatomy of the pancreas and nearby structures relevant to staging with correlation on CT and MRI, including discussion of optimum imaging technique - Review of TNM staging system for pancreatic adenocarcinoma (AJCC 7th ed) - Overview of classes of non-resectable pancreatic cancer (borderline resectable, locally advanced, metastatic) and current staging methods - Illustration of common and uncommon pathways of tumor spread and sites of metastases with multimodality imaging - Discussion of treatment options defined by extent of disease, including roles of chemotherapy, molecular targeted therapy, and radiotherapy - Case-based review of side effects, complications, and treatment response  

http://abstract.rsna.org/uploads/2014/14012414/14012414_nrrl.pdf

Gilbert, J, Shinagare, A, Jagannathan, J, Wolpin, B, Ramaiya, N, Rosenthal, M, Beyond the Whipple Resection: What the Radiologist Needs to Know about the Multimodality Imaging of Borderline Resectable, Locally Advanced, and Metastatic Pancreatic Adenocarcinomas.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14012414.html