1. Describe the associated radiologic findings in diseases of decreased bone mineralization in children.
2. Distinguish the different diseases of decreased bone mineralization based on the imaging findings.
3. Understand the pathophysiology behind the radiologic appearance of these diseases.
Case Outline:
1) Rickets
a. Abnormal Vitamin D Metabolism (vit D deficiency, hepatic or renal origin)
b. Hypophosphatemic Rickets (phosphate loss due to renal tubular disorders)
2) Osteogenesis Imperfecta- 4 types
3) Gorham Disease
4) Congenital Syphilis
5) Scurvy
6) Copper insufficiency with liver disease and prolonged alimentation
7) Hypophosphatasia
8) Juvenile (idiopathic) Osteoporosis
9) Metabolic Bone Disease of Prematurity
Favinger, J,
Done, S,
Parnell, S,
Where's the Bone?: Diseases of Bone Demineralization in Children. Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL.
http://archive.rsna.org/2014/14012342.html