Tatsuyuki Tonan MD, Presenter: Nothing to Disclose

Kiminori Fujimoto MD, PhD, Abstract Co-Author: Nothing to Disclose

Tsutomu Kumabe, Abstract Co-Author: Nothing to Disclose

Shuji Nagata MD, Abstract Co-Author: Nothing to Disclose

Akiko Sumi MD, Abstract Co-Author: Nothing to Disclose

Masafumi Uchida MD, PhD, Abstract Co-Author: Nothing to Disclose

Osamu Nakashima, Abstract Co-Author: Nothing to Disclose

Koji Okuda, Abstract Co-Author: Nothing to Disclose

Toshi Abe MD, Abstract Co-Author: Nothing to Disclose

1. To understand two enhancement patterns (types of gradual and persistent) of hepatic tumors on EOB-enhanced MRI for predicting pathologic characteristics (distribution and amount of intratumoral fibrous stroma, micro-vessels, and tumor cell). 2. To illustrate various tumors with each enhancement pattern.

Gd-EOB-DTPA combines the properties of a conventional non-specific extracellular and a hepatocyte-specific contrast agent. In this presentation, we evaluate the pathological characteristics of various hepatic tumors, which show extracellular enhancement effect on hepatobiliary phase, such as cholagiocellular carcinoma, cholangiolocellular carcinoma, sarcomatous/sclerosing hepatocellular carcinoma, neuroendocrine tumors including carcinoid tumor and carcinoma, and primary hepatic lymphoma. They have various dynamic enhancement pattern (i.e., gradual and persistent enhancement) and variable delayed extracellular enhancement pattern on hepatobiliary phase according to various distribution and amount of intratumoral fibrous stroma, micro-vessels and tumor cell. While these imaging findings are not specific finding, to understand these imaging findings are helpful in diagnosis of hepatic tumors. Furthermore, evaluation of the intratumoral fibrous stroma may aid prognostic prediction of hepatic malignant tumor.

http://abstract.rsna.org/uploads/2014/14012287/14012287_rgip.pdf

Tonan, T, Fujimoto, K, Kumabe, T, Nagata, S, Sumi, A, Uchida, M, Nakashima, O, Okuda, K, Abe, T, Spectrum of Hepatic Tumors with Delayed Extracellular Enhancement Effect on Hepatobiliary Phase of EOB-enhanced MRI: MR-pathologic Correlation.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14012287.html