Yu Htwe MD, Presenter: Nothing to Disclose

Matthew D. Cham MD, Abstract Co-Author: Nothing to Disclose

Rowena Yip MPH, Abstract Co-Author: Nothing to Disclose

Artit C. Jirapatnakul PhD, Abstract Co-Author: Nothing to Disclose

David F. Yankelevitz MD, Abstract Co-Author: Research Grant, AstraZeneca PLC Royalties, General Electric Company

Claudia I. Henschke MD, PhD, Abstract Co-Author: Nothing to Disclose

To compare the Ordinal Scores with the Agatston Scores obtained on non-gated low-dose CT scans

636 asymptomatic participants (women 416, men 220, mean age 55 years) had low-dose CT screening scans . Each participant was graded as to the extent of coronary artery calcification (CAC) in the 4 arteries (left main, left anterior decending, circumflex and right) and received a Ordinal Score between 0 and 12. Standard software was used to obtain the Agatston Score, but it could not be obtained on 5 participants, reducing the total number for evaluation of 631. Each participant was classified into 1 of 3 Ordinal Score Categories (0, 1-3, 4-12) and 1 of 3 standard Agatston Score Categories (0, 1-400, 400+).

The Ordinal Score of 0 was in agreement with the Agatston Score of 0 in 440 (70%) of the 631 participants, the Ordinal Score of 1-3 was in agreement with the Agatston Score of 11-400 in 78 (12%) participants, and the Ordinal Score of 4-12 was in agreement with the Agatston Score of 400+ in 21 (3%) participants.  Thus there was agreement in 539 (85%) of the 631 participants.  In 36 of the remaining 92 participants, the Agatston Score was 0 because the calcifications that were actually present were too small to meet the criteria of acceptance by the Agatston software.  The remaining 56 (9%) of the 631 participants differed only by 1 category.  Overall, the Ordinal Score Categories showed excellent agreement (weighted kappa of 0.83- 95% CI: 0.79-0.88) with the Agatston Score Categories.

The use of the Ordinal Score is readily obtained on low-dose CT scans.  It shows excellent agreement with the Agatston Score and is thus useful for risk stratification of coronary artery disease.

It is important to provide information obtained from low-dose CT scan about coronary artery disease by providing either the Ordinal or Agatston Scores.

Htwe, Y, Cham, M, Yip, R, Jirapatnakul, A, Yankelevitz, D, Henschke, C, Coronary Artery Calcification on Low-dose Computed Tomography: Comparison of Agatston and Ordinal Scores.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14011721.html