Tahreema Nihad Hashmi Matin MBBS, Presenter: Nothing to Disclose

Xiaojun Xu MSc, DPhil, Abstract Co-Author: Nothing to Disclose

Nassim Parvizi MBBS, BSC, Abstract Co-Author: Nothing to Disclose

Tom Doel DPhil, Abstract Co-Author: Nothing to Disclose

Jennifer Lee, Abstract Co-Author: Nothing to Disclose

Najib Rahman MSc, DPhil, Abstract Co-Author: Nothing to Disclose

Annabel Nickol, Abstract Co-Author: Nothing to Disclose

Vicente Grau PhD, Abstract Co-Author: Nothing to Disclose

Fergus Vincent Gleeson MBBS, Abstract Co-Author: Alliance Medical Ltd Consultant

To describe hyperpolarised xenon MRI (Xe-MRI) at 1.5T, a novel regional functional imaging technique.

A. Limitations of current lung function assessment tools B: Description of Xe-MRI technique including hyperpolarisation method, choice of sequences and typical examination pathway C: Radiological features of Xe-MRI in healthy volunteers and patients with chronic respiratory disease D: Description of novel Xe-MRI data analysis methodology including regional segmentation and multi-modality co-registration E: Potential utility of Xe-MRI and role in clinical care Summary: Current methods for assessing lung function are inadequate. Imaging data from 30 prospectively enrolled healthy volunteers, and patients with chronic respiratory disease are used to illustrate the potential of Xe-MRI to offer comprehensive evaluation of regional lung function. Establishing Xe-MRI will lead to a better understanding of regional lung disease pathophysiology and enable individual-tailored treatments by improved assessment of therapeutic response.

http://abstract.rsna.org/uploads/2014/14011483/14011483_q1ti.pdf

Matin, T, Xu, X, Parvizi, N, Doel, T, Lee, J, Rahman, N, Nickol, A, Grau, V, Gleeson, F, Hyperpolarised Xenon MRI—A New Functional Imaging Technique in Respiratory Medicine.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14011483.html