Taner Arpaci, Presenter: Nothing to Disclose

Anil Ozgur, Abstract Co-Author: Nothing to Disclose

Tugana Akbas MD, Abstract Co-Author: Nothing to Disclose

Rabia Arpaci, Abstract Co-Author: Nothing to Disclose

gamze ugurluer, Abstract Co-Author: Nothing to Disclose

To review the neuroimaging findings during childhood leukemia and lymphoma or after the treatments. To discuss the diagnostic approach and differential diagnosis.  

The neuroimaging features of childhood leukemia and lymphoma have been classified into three main categories.  I. Central nervous system findings of primary malignancy -Cerebrovascular disease (Craniospinal hemorrhage, cerebral infarction) -Central nervous system involvement (Infiltration of leptomeninges, bone marrow, orbit, spine) II. Complications of therapeutic procedures -Radiation therapy (White matter disease, cerebral volume loss and hydrocephalus, cryptic vascular malformations) -Chemotherapy and bone marrow transplantation (Dural sinus thrombosis, white matter disease, posterior reversible leukoencephalopathy syndrome) III. Infectious diseases due to immunosuppression -Fungi (Mucormycosis, aspergillus, candida) Summary Recent developments in the treatment of pediatric hematologic neoplasms have improved the prognosis but resulted in an increased incidence of neurologic complications. The awareness of the imaging features is essential for early diagnosis and proper treatment of neurologic symptoms to increase survival in pediatric patients with leukemia and lymphoma.  

http://abstract.rsna.org/uploads/2014/14011426/14011426_g16d.pdf

Arpaci, T, Ozgur, A, Akbas, T, Arpaci, R, ugurluer, g, Neuroimaging in Childhood Leukemia and Lymphoma: A Pictorial Review.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14011426.html