Maha Hussein Helal MD, Presenter: Nothing to Disclose

Dorria Saleh Salem MD, Abstract Co-Author: Nothing to Disclose

Basma El Kalaawy MBBCh, Abstract Co-Author: Nothing to Disclose

Lamia Adel MD, Abstract Co-Author: Nothing to Disclose

Sahar Mansour MD, Abstract Co-Author: Nothing to Disclose

Nadia Mokhtar MD, Abstract Co-Author: Nothing to Disclose

Nelly Alieldin MD, Abstract Co-Author: Nothing to Disclose

nagat mansour khalifa, Abstract Co-Author: Nothing to Disclose

Noha Abdel Shafey MD, Abstract Co-Author: Nothing to Disclose

Rasha Mohamed Kamal MD, Abstract Co-Author: Nothing to Disclose

Omnia Mokhtar MD, Abstract Co-Author: Nothing to Disclose

we aimed to elucidate the role of recent advances in digital mammography, versus 3D breast ultrasound in the staging of breast cancer prior management.

This retrospective analysis with ethics committee approval included 115 masses in 103 cases. Evaluation methods included regular digital mammography, 3-D tomosynthesis, contrast enhanced mammography and 3D breast ultrasound. For mammography acquisition, a combined technique (2D+3D imaging) that acquires a traditional digital mammogram and a tomosynthesis scan in the same compression is performed. For applying contrast-enhanced images: low and high energy exposures were taken in the same projections after IV injection of contrast agent. Evaluated masses were biopsied and proved malignancy (70 masses) were further evaluated regarding lesions’ extension, size, multiplicity and related calcifications in correlation with data provided with 2D and automated 3D ultrasound examinations. Pathological specimen was the standard reference.

Comparable estimation to the pathology extension was provided by tomosynthesis (n=58, 83%) and 3D ultrasound (n=56, 80%) followed by contrast-enhanced (n=32, 46%) and regular mammography (n=51, 73%). Contrast-enhanced mammography presented the least assessment for calcifications, yet the most accurate size estimation with a median value of 0.4 compared to 0.5 and 1.5 for tomosynthesis and regular mammography respectively. Multiplicity was better demonstrated by contrast mammography with sensitivity of 92% followed by 3D ultrasound (87%), then tomosynthesis (77%) and regular mammography (54%). An accuracy of 92% presented by combined analysis of the advanced mammography applications and the 3D automated ultrasound in the pre-operative evaluation of breast cancer.

Digital mammogram with advanced applications (tomosynthesis and contrast-enhanced imaging) together with 2D and 3D automated ultrasound provide an utmost evaluation and proper staging of breast cancer.

Digital mammography (DM) is still limited by overlapped densities that may provide false negative/positive diagnosis. Advanced applications of DM: tomosynthesis and contrast-enhanced mammography aided by the application of 2D and automated 3D ultrasound imaging represent the perfect mélange for proper prognosis assessment and prior management precise estimation.

Helal, M, Salem, D, El Kalaawy, B, Adel, L, Mansour, S, Mokhtar, N, Alieldin, N, khalifa, n, Abdel Shafey, N, Kamal, R, Mokhtar, O, The Additive Role of 3D Reconstructed Ultrasound to the New Technologies of Digital Mammography in the Proper Assessment of Breast Cancer .  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14011070.html