Min-Yung Chang MD, Presenter: Nothing to Disclose

Sung Yoon Park, Abstract Co-Author: Nothing to Disclose

Young Eun Yoon, Abstract Co-Author: Nothing to Disclose

Woong Kyu Han, Abstract Co-Author: Nothing to Disclose

Dae Chul Jung, Abstract Co-Author: Nothing to Disclose

Young Taik Oh MD, Abstract Co-Author: Nothing to Disclose

To analyze whether the presence or amount of abdominal aortic calcification (AAC) could predict renal function impairment of donors after kidney transplantation

Between 2010 and 2013, 287 donors undergoing nephrectomy were enrolled. The calcium score (CS) of AAC was quantitatively measured with Agatston score on CT angiography. The donors were divided into AAC (CS>0, n=238) and non-AAC (CS=0, n=49) groups. The propensity score matching was conducted in terms of age, sex, and body mass index. The estimating glomerular filtration rate (eGFR) was measured before, and 1-week, 1-month, 3-month, and 6-month after transplantation. Between two groups, pre- and postoperative eGFRs were compared before and after propensity score matching, respectively.

The mean CS was 185.5 ± 263.3 in ACC and 0 in non-ACC (p<0.05). Before propensity score matching, all of pre- and postoperative eGFRs were different between two groups (p<0.05). After propensity score matching, those differences of eGFR disappeared (p>0.05). The presence of AAC was not an indicator for predicting renal function impairment under propensity score matching (p>0.05). However, among AAC group, CS more than 100 was related to renal function impairment as compared to CS of 100 or less (p=0.035). In multivariable analysis, CS more than 100 (OR=12.4, p=0.017) and preoperative eGFR (OR=0.829, p=0.001) were associated with the occurrence of chronic kidney disease (CKD; eGFR<60mL/min/1.73 m2 at 6-month postoperatively)

The calcium score more than 100 of abdominal aorta may be a predictor of CKD occurrence after kidney transplantation although the presence of abdominal aortic calcification itself may not be related to postoperative renal function impairment.

In renal donors, preoperative CT evaluation in terms of abdominal aortic calcification may help predict renal function impairment after kidney transplantation, which information may allow clinicians to plan the follow-up strategy for donors

Chang, M, Park, S, Yoon, Y, Han, W, Jung, D, Oh, Y, Prediction of Renal Function Impairment of Donors after Kidney Transplantation: Analysis by Using Abdominal Aortic Calcification under Propensity Score Matching.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14010188.html