Lorene Elaine Romine MD, Presenter: Nothing to Disclose

Tracy Anton BS, Abstract Co-Author: Nothing to Disclose

Gladys Ramos MD, Abstract Co-Author: Nothing to Disclose

Dolores Helen Pretorius MD, Abstract Co-Author: Software support, Koninklijke Philips NV Software support, General Electric Company

1. Review the spectrum of abnormalities that may be present when a pregnant woman presents with an elevated serum AFP at aneuploidy screening. 2. Identify key imaging features that will aid in appropriate diagnosis.

1. Fetal a. Neural Tube Defects i. Myelomeningocele ii. Encephalocele iii. Anencephaly b. Abdominal Wall Defects i. Gastroschisis ii. Omphalocele iii. Limb body wall iv. Bladder exstrophy c. Amniotic band syndrome d. Renal anomalies i. Congenital nephrosis ii. Renal agenesis e. Proximal bowel obstruction i. Esophageal atresia ii. Duodenal atresia f. Tumors i. Sacrococcygeal teratoma ii. Oropharyngeal teratoma 2. Placental a. Abruption b. Accreta c. Chorioangioma d. Infarction e. Hemorrhage 3. Maternal a. HCC b. Hepatitis c. Ovarian germ-cell neoplasm 4. Other Considerations a. Off-dates b. Multiples c. Demise d. Skin lesions e. Parvovirus infection

http://abstract.rsna.org/uploads/2014/14010121/14010121_lkh3.pdf

Romine, L, Anton, T, Ramos, G, Pretorius, D, More than Neural Tube Defects: Spectrum of Pathology to Consider with Elevated Maternal Serum AFP.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14010121.html